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https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/33d05f6a-4815-4d0c-a3c5-487bcf869b02/ESCs+on+Micropatterns.jpg https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/1ad53152-ed15-40da-92f0-c1711e1f71d6/MAX_2023-10-31-Schwann+cells+on+2D+TCP+with+and+without+SAG-Ac+Tubulin+488-Gama+Tub+647-Phalloidin+TRITC-DAPI-63X.lif+-+No+SAG-4.png https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/81dc708d-d91e-4de6-b10a-f0072d97c512/Picture3.jpg https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/c66a4756-7c72-4957-9b55-4064f39e185b/Picture1.png https://www.cellcircuitbio.com/new-page-1-2 daily 0.75 2026-03-27 https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/6fad2ea0-68f3-45c3-8c04-61e57650c17f/MAX_PLD001_hNPCsinHELP_Day7_DAPITUBB3Phal-63x.lif+-+RGD-PLD_BZA_63X_2a.png https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/9e3e4bbe-227b-44fe-b8e9-23ff6c660945/MAX_2023-12-20-Betty%27s+sample-Static+and+Dynamic+groups.lif+-+Dynamic-488VeCad-RP-647Phalloidin-Marked13.png https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/51f6db84-6619-4bcf-829b-de517e1e74c2/MAX_GBM072-2D-U87-D7-COL1+488-+Bcat+488-Col6+488-Phalloidin.lif+-+COL6-488-Phalloidin-A1.png https://www.cellcircuitbio.com/case-studies-1 daily 0.75 2026-04-01 https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/0247f439-bace-4491-baaa-c3509feeee05/hNSCs+on+micropattern.png Morphology & Phenotyping https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/8c5bffba-11fa-4e2d-b106-978f6f77ee86/mESCs.png Morphology & Phenotyping https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/6cfc2a32-0ad8-4f2f-a40d-1fc712921d4f/IFSCs-Ca.png Morphology & Phenotyping https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/88add38b-7b4e-4a13-a3cd-7db0d926f48b/mESCs+Arrays.png Morphology & Phenotyping https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/3681ff58-1f05-4985-b8f5-99128907b93e/mESCs.png Morphology & Phenotyping Fluorescence imaging of murine embryonic stem cells expressing an OCT4-GFP reporter cultured on various ECM substrates (gelatin, fibronectin, collagen I, and laminin-111) under +LIF and −LIF conditions. Nuclei are stained with DAPI (blue) and the actin cytoskeleton with phalloidin (red). Distinct ECM- and media-dependent changes in stemness and colony morphology are evident after 5 days of culture. https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/7fa6603e-ab3e-46d9-8a39-a3788a960c2b/Purple+and+White+Modern+Problem+and+Solution+Table+Graph+%281%29.png Morphology & Phenotyping - Build it. It all begins with an idea. Maybe you want to launch a business. Maybe you want to turn a hobby into something more. Or maybe you have a creative project to share with the world. Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/a8d79210-36a1-4c2d-9ada-9763222301e1/hNSCs+on+micropattern.png Morphology & Phenotyping Fluorescence imaging of human neural stem cells cultured on ECM micropatterned substrates (50 μm line and circular geometries) for 1 week in the absence of differentiation inducers. Neuronal marker TUBB3 (green), stem cell marker SOX2 (red), and nuclei (DAPI, blue) reveal geometry-dependent differences in cell organization and phenotype. Line patterns promote aligned, elongated morphologies with increased neuronal features, while circular patterns maintain confined, stem-like cell states. https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/3fac011c-fd89-44cb-a6ff-635256306fb9/MP-2.png Morphology & Phenotyping - Build it. It all begins with an idea. Maybe you want to launch a business. Maybe you want to turn a hobby into something more. Or maybe you have a creative project to share with the world. Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/8d714f04-d203-4dd2-97fe-eed326eca6d7/mESCs+Arrays.png Morphology & Phenotyping High-throughput fluorescence imaging of murine embryonic stem cells cultured on 2 × 2 cm submicron-patterned arrays comprising 64 distinct structures, pre-coated with different ECM ligand conditions (Condition A, Condition B, and controls), at day 5 post-seeding. OCT4 expression is visualized via a GFP reporter (green), with nuclei labeled by DAPI (blue) and F-actin by phalloidin (red). Multiparametric analysis reveals condition-dependent differences in cell distribution, morphology, and stemness across the patterned array. https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/492b1f29-8dd4-4a9b-b15a-ea72d2f5e730/MP-3.png Morphology & Phenotyping https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/6447b5f8-8b83-459a-89a7-e8e8cbed44ca/IFSCs-Ca.png Morphology & Phenotyping Fluorescence imaging of human epidermal interfollicular stem cells cultured on homogeneous and nanopatterned ECM substrates under defined calcium conditions (Condition A and Condition B). Cells are labeled for nuclei (DAPI, blue), actin cytoskeleton (phalloidin, red), and differentiation marker involucrin (IVL, green). Distinct differences in cell morphology, cytoskeletal organization, and phenotypic state are observed across substrate and calcium conditions. https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/c811c00f-cb3a-42eb-ad5e-5f5748a1b57a/MP-4.png Morphology & Phenotyping - Build it. It all begins with an idea. Maybe you want to launch a business. Maybe you want to turn a hobby into something more. Or maybe you have a creative project to share with the world. Whatever it is, the way you tell your story online can make all the difference. https://www.cellcircuitbio.com/case-studies-1-1 daily 0.75 2026-04-01 https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/488e7666-2e24-4435-b6e6-917241fc009a/DSC2-HaCaT.png Spatial Organization https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/daaf18b7-43c6-46d8-a695-10fa26df5f99/hNSCs+on+nanopattern.png Spatial Organization https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/c9cd8b5b-06bf-415b-adf0-1dd318168c00/Hacat+HDs.png Spatial Organization https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/68003f22-4320-4320-8ea9-4af541d2d5a2/DSC2-HaCaT.png Spatial Organization High-resolution fluorescence imaging of desmosomal structures in HaCaT keratinocytes. Desmoplakin (DP, red) and desmocollin-2 (DSC2-GFP, green) localize at cell-cell junctions, highlighting the organization of desmosomal adhesion complexes. Insets show higher magnification views of protein clustering and co-localization. This imaging approach enables detailed visualization of epithelial cell-cell interactions at subcellular resolution. Scale bars: 2 μm (insets), 20 μm (overview). https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/f85cb6ee-4028-4b46-822d-b2bfaec6a37d/SO-1.png Spatial Organization - Build it. It all begins with an idea. Maybe you want to launch a business. Maybe you want to turn a hobby into something more. Or maybe you have a creative project to share with the world. Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/c5495312-7e00-4069-8df7-3d8cd8b8cc2c/hNSCs+on+nanopattern.png Spatial Organization High-resolution fluorescence imaging of human neural stem cells cultured on nanopatterned ECM substrates. Laminin-based nanopatterns (fluorescently labeled, red) define the underlying microenvironment, while neuronal marker TUBB3 (green) and nuclei (DAPI) reveal cell morphology and early differentiation after 24 hours. Cells exhibit directed neurite extension and localized interactions with nanoscale ECM features, highlighting the role of matrix patterning in regulating cell behavior. https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/d1a85fef-ed9f-4840-ba9c-22670de768c0/SO-2.png Spatial Organization https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/05b25605-3f9f-49d2-886e-d5c1a80508f0/Hacat+HDs.png Spatial Organization Confocal fluorescence imaging of HaCaT cells cultured on nanopatterned substrates with varying feature sizes (100–1000 nm) after 12 hours. (a) Co-localization of Collagen XVII (green) and α6 integrin (red), highlighting organization at the cell–ECM interface. (b) Co-localization of pan-cytokeratin (green) and α6 integrin (red), illustrating cytoskeletal interactions. Merged images and intensity profiles demonstrate nanopattern-dependent spatial organization of adhesion and cytoskeletal proteins. Scale bars: 5 μm. https://images.squarespace-cdn.com/content/v1/6954c3acf0d40f70957a519c/cc1317c0-42fa-451a-a0d6-6e064b336537/SO-3+%281%29.png Spatial Organization - Build it. It all begins with an idea. Maybe you want to launch a business. Maybe you want to turn a hobby into something more. Or maybe you have a creative project to share with the world. 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